Cytokines

Proteins

Cytokines

Secreted signalling proteins produced in CHO, HEK293, insect and yeast host systems

Cytokines are small secreted proteins that regulate cell signalling in the immune system and beyond. They bind specific receptors on target cells and trigger transduction pathways that control gene expression.

How it works

Secreted Signalling Proteins

Our cytokines are produced recombinantly by expressing the target gene in a host cell line, most often CHO or HEK293, with smaller numbers produced in insect cells or yeast. The range is supplied unconjugated, ready for use in cell culture and functional assay work.

Category benefits

Why use our cytokines?

✓ A choice of expression systems
Our cytokine range is produced across CHO, HEK293, insect and yeast host systems, so you can match the format to your assay.
✓ Coverage across signalling pathways
The range spans interleukins such as IL-2, IL-4, IL-6 and IL-7, colony-stimulating factors including GM-CSF, and receptor subunits such as CD25 and CD122.
✓ Unconjugated for functional use
Every cytokine in our range is supplied unconjugated, suited to cell culture, differentiation and functional bioassay work without further processing.
✓ Purity and QC data supplied
Each product datasheet states the expression host, purity and, where available, bioactivity data confirming functional performance.
Where they're used

Typical applications

✓ Cell culture and differentiation
Cytokines and growth factors in our range support cell culture, differentiation protocols and functional bioassay work.
✓ Functional bioassays
Cytokines such as IL-2 are used in receptor-driven proliferation assays to confirm bioactivity ahead of use in a study.
✓ ELISA calibration and standards
Recombinant cytokines serve as calibrators and standards for ELISA and other quantitative immunoassays.
✓ Growth factor and receptor signalling studies
Growth factors in our range, including Hepatocyte Growth Factor, FLT3 Ligand, Follistatin and Angiopoietin-2, support receptor binding and signalling research.

Need help choosing a cytokine?

Contact our technical support team for help selecting the right cytokine, host system or format for your assay. Each product page includes a downloadable datasheet and SDS, with dispatch on overnight priority shipping with gel ice packs.

Looking for more cytokines?

Browse the full cytokines and growth factors range, including interleukins, colony-stimulating factors and receptor subunits.

 View cytokine research insights

For Research Use Only. Not for use in diagnostic procedures.

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