Cell surface proteins

✓	One supplier for a wide target list With 100+ recombinant targets in the range, spanning CD markers such as CD20, CD38 and CD80 and receptors including CXCR4, CTLA4 and c-MET (HGFR), sourcing multiple related targets from a single supplier is straightforward.
✓	A choice of expression host Most of the range is produced in HEK293 cells, with a portion produced in CHO cells, insect cells or P.pastoris depending on the target.
✓	Untagged and Fc-tagged format options Selected targets, including CD31 (PECAM1) and CD155, are available with an Fc-tag alongside the untagged format, giving a choice suited to different assay setups.
✓	Documentation and purity data supplied Each product page provides a downloadable datasheet and safety data sheet, with purity reported on the datasheet using methods such as SDS-PAGE.

✓	Receptor-ligand binding studies The ECD format used across most of the range, in some cases paired with an Fc-tag, suits binding and kinetics work such as ELISA or surface plasmon resonance.
✓	Cell-based functional assays Fc-fusion proteins in the range have been used to coat assay surfaces for functional cell binding work, as with CD137-Fc coated plates used to assess microglial cell attachment.
✓	Structural and biochemical characterisation Purity data reported on product datasheets, including SDS-PAGE analysis, supports use of the proteins in biochemical and structural work.
✓	Assay screening through to scale-up Pack sizes across the range run from 5 µg up to 100 g, allowing selection of quantity for pilot screening through to larger-scale assay work.

Cell Surface Proteins