| Host: |
HEK293 |
| Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human Tissue factor pathway inhibitor 2-protein was developed from hek293. For use in research applications. |
| Conjugation: |
Unconjugated |
| Formulation: |
Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Dilution Range: |
Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: |
Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: |
The activity was tested by the ability to inhibit trypsin cleavage of a fluorogenic peptide substrate Mca-RPKPVE-Nval-WRKDnp-NH2, with a calculated ED50 < 2.5nM NA |
| Gene Symbol: |
TFPI2 |
| Gene ID: |
7980 |
| Uniprot ID: |
TFPI2_HUMAN |
| Immunogen Region: |
ASP23-LYS213 |
| Immunogen: |
Optimized DNA sequence encoding mature chain of human Tissue factor pathway inhibitor 2-TFPI2 (ASP23-LYS213) including a C-terminal His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy. |
| Function | May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin. |
| Protein Name | Tissue Factor Pathway Inhibitor 2Tfpi-2Placental Protein 5Pp5 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Tissue Factor Pathway Inhibitor 2 proteinTfpi-2 proteinPlacental Protein 5 proteinPp5 proteinTFPI2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
