Monoclonal antibodies(mAb, moAb) are molecules, produced in laboratories and serve the purpose of enhancing, restoring or mimic the attack of the immune system on cancer cells. They are made by cloning a specific white blood cell and all subsequent mAbs can be traced back to a unique parent cell. When an antigen is introduced to either a mouse or a rabbit and polyclonal B cells are fused from the spleen to the myeloma, a hybridoma is created. That hybridoma is then cultured in order to continue with antibody production. They can also be designed to have monovalent affinity.