Human Tissue factor pathway inhibitor 2 protein (Recombinant) (STJP000287)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encoding mature chain of mouse Tissue factor pathway inhibitor 2-TFPI2 (LEU23-LYS211) including a C-terminal His tag was expressed in HEK293 cells. NA
General Information
| Short Description | Recombinant-Human Tissue factor pathway inhibitor 2-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Formulation | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Target Information
| Gene Symbol | Tfpi2 |
| Gene ID | 21789 |
| Uniprot ID | TFPI2_MOUSE |
| Immunogen | Optimized DNA sequence encoding mature chain of mouse Tissue factor pathway inhibitor 2-TFPI2 (LEU23-LYS211) including a C-terminal His tag was expressed in HEK293 cells. NA |
| Immunogen Region | LEU23-LYS211 |
Additional Info
| Tissue Specificity | Highly expressed in placenta. Also expressed in liver and kidney. |
| Function | May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin. |
| Protein Name | Tissue Factor Pathway Inhibitor 2Tfpi-2 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Tissue Factor Pathway Inhibitor 2 proteinTfpi-2 proteinTfpi2 protein |
Information sourced from Uniprot.org