Human CD66b (CEACAM8) protein (Recombinant) (STJP000513)

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STJP000513
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Short Description :Recombinant-Human CD66b (CEACAM8)-protein was developed from hek293. For use in research applications.
Host:HEK293
Note:STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Formulation:0.2 Mu m filtered PBS solution, pH7.2.
Storage Instruction:Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin:Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity:The activity was tested by immobilized recombinant CD66a (10ug/ml) ability to bind recombinant human CD66b in functional ELISA. NA
Gene Symbol:CEACAM8
Gene ID:1088
Uniprot ID:CEAM8_HUMAN
Immunogen:Optimized DNA sequence encoding extracellular domain of human CD66bincluding a C-terminal 6His tag was expressed in HEK293 cells. NA
Immunogen Region:ECD
Tissue Specificity Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
Post Translational Modifications Glycosylated.
Function Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.
Protein Name Cell Adhesion Molecule Ceacam8
Cd67 Antigen
Carcinoembryonic Antigen Cgm6
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8
Cea Cell Adhesion Molecule 8
Non-Specific Cross-Reacting Antigen Nca-95
Cd Antigen Cd66b
Database Links Reactome: R-HSA-1566977
Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Cell Surface
Alternative Protein Names Cell Adhesion Molecule Ceacam8 protein
Cd67 Antigen protein
Carcinoembryonic Antigen Cgm6 protein
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 protein
Cea Cell Adhesion Molecule 8 protein
Non-Specific Cross-Reacting Antigen Nca-95 protein
Cd Antigen Cd66b protein
CEACAM8 protein
CGM6 protein

Information sourced from Uniprot.org

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