Post Translational Modifications

Primary Antibodies

Post Translational Modifications

Post-translational modifications, or PTMs, are essential eukaryotic mechanisms used to diversify protein functions and coordinate signalling networks. They are accomplished by covalent addition of protein functional groups, degradation of whole proteins, or proteolytic cleavage of regulatory subunits.

Browse all PTM antibodies
About PTMs How PTMs work Modification types
Product overview

What are post-translational modifications?

St John's Laboratory lists thousands of antibodies raised against specific post-translationally modified protein sites.

  • Diversify protein function PTMs are essential eukaryotic mechanisms used to diversify protein functions beyond what is encoded at the genetic level.
  • Coordinate signalling networks By modifying specific residues, PTMs help coordinate signalling networks within the cell.
  • Multiple mechanisms PTMs are accomplished by covalent addition of protein functional groups, degradation of whole proteins, or proteolytic cleavage of regulatory subunits.
Mechanisms

How PTMs work

A post-translational modification changes a protein after it has been synthesised, either by covalently attaching a functional group to a specific residue, by degrading the whole protein, or by proteolytically cleaving off a regulatory subunit.

Modification types

Modification types

Antibodies on this page target specific modified residues, including the following modification types.

Acetylation Methylation

Need help choosing an antibody?

Contact our technical support team for help selecting an antibody for your modified target of interest. Each product page includes a downloadable datasheet and SDS, with dispatch on overnight priority shipping with gel ice packs.

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