• The 2 NA-O-methylcytidine (Cm) Rabbit monoclonal antibody (STJ11104061) are tested in Dot Blot against 2 NA-O-methylcytidine and unmodified cytidine. 2 NA-O-methylcytidine :Biotin-5 NA CGATAACCACTAGT (Cm) 3 NA unmodified cytosine:Biotin-5 NA CGATAACCACTAGTC3 NA

Anti-2 NA-O-methylcytidine/Cm antibody [S4061RM] (STJ11104061)

SKU:
STJ11104061

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Host: Rabbit
Reactivity: Species independent
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-2 O-methylcytidine/Cm is suitable for use in research applications.
Clonality: Monoclonal
Clone ID: S4061RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: DB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunogen: Cm
Immunogen Sequence: Cm conjugated to KLH
Background RNA methylation plays a significant regulatory role in various of physiological activities. 2 NA-O-methylcytidine (Cm) is one of the representative 2 NA-O-methylation and base-methylation modified epigenetic marks of RNA. 2 NA-O-Methylcytidine is derivative of the nucleoside residue cytidine with a methyl group attached to the 2 NA-oxygen position. 2 NA-O-methylcytidine was found to be related to various diseases including cancer, and it might have great potential to be novel biomarkers for detection of breast cancer in the early stage. In addition, 2 NA-O-methylcytidine showed as an inhibitor of RNA polymerase from the hepatitis C virus (HCV). And 2 NA-O-methylcytidine was involved in plant stress responses.

Information sourced from Uniprot.org

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