Anti-2 NA-O-methylcytidine/Cm antibody [S4061RM] (STJ11104061)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal 2 O-methylcytidine/Cm antibody for use in DB and ELISA in species independent samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | DB/ELISA |
| Host | Rabbit |
| Reactivity | Species Independent |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4061RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | DB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Immunogen Sequence | Cm conjugated to KLH |
| Specificity | Cm |
Additional Info
| Background | RNA methylation plays a significant regulatory role in various of physiological activities. 2 NA-O-methylcytidine (Cm) is one of the representative 2 NA-O-methylation and base-methylation modified epigenetic marks of RNA. 2 NA-O-Methylcytidine is derivative of the nucleoside residue cytidine with a methyl group attached to the 2 NA-oxygen position. 2 NA-O-methylcytidine was found to be related to various diseases including cancer, and it might have great potential to be novel biomarkers for detection of breast cancer in the early stage. In addition, 2 NA-O-methylcytidine showed as an inhibitor of RNA polymerase from the hepatitis C virus (HCV). And 2 NA-O-methylcytidine was involved in plant stress responses. |
Information sourced from Uniprot.org