• Anti-14-3-3 alpha+beta antibody [SM5110] (STJA0005110)
  • Anti-14-3-3 alpha+beta antibody [SM5110] (STJA0005110)
  • Anti-14-3-3 alpha+beta antibody [SM5110] (STJA0005110)
  • Anti-14-3-3 alpha+beta antibody [SM5110] (STJA0005110)
  • Anti-14-3-3 alpha+beta antibody [SM5110] (STJA0005110)
  • Anti-14-3-3 alpha+beta antibody [SM5110] (STJA0005110)

Anti-14-3-3 alpha+beta antibody [SM5110] (STJA0005110)

SKU:
STJA0005110

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Host: Mouse
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-14-3-3 alpha+beta is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: SM5110
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol.
Purification: Affinity purification
Dilution Range: IHC/IF (H, M, R) 1:500-1:1000/1:500-1:1000
Storage Instruction: Store at-20C for up to one year, and avoid repeated freeze-thaw cycles.
Gene Symbol: Ywhab
Gene ID: 54401
Uniprot ID: 1433B_MOUSE
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse 14-3-3 alpha + beta
Function Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
Protein Name 14-3-3 Protein Beta/Alpha
Protein Kinase C Inhibitor Protein 1
Kcip-1 Cleaved Into - 14-3-3 Protein Beta/Alpha - N-Terminally Processed
Database Links Reactome: R-MMU-111447
Reactome: -MMU-165159
Reactome: -MMU-166208
Reactome: -MMU-170968
Reactome: -MMU-2028269
Reactome: -MMU-392517
Reactome: -MMU-450385
Reactome: -MMU-450513
Reactome: -MMU-5625740
Reactome: -MMU-5628897
Reactome: -MMU-5673000
Reactome: -MMU-5674135
Reactome: -MMU-5675221
Reactome: -MMU-75035
Reactome: -MMU-9614399
Cellular Localisation Cytoplasm
Melanosome
Alternative Antibody Names Anti-14-3-3 Protein Beta/Alpha antibody
Anti-Protein Kinase C Inhibitor Protein 1 antibody
Anti-Kcip-1 Cleaved Into - 14-3-3 Protein Beta/Alpha - N-Terminally Processed antibody
Anti-Ywhab antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance