Anti-14-3-3 protein eta antibody (Full-Length) [3G12] (STJA0040760)

Name: Anti-14-3-3 protein eta antibody (Full-Length) [3G12] (STJA0040760)
SKU: STJA0040760-100
Price: 528.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostMouse

ConjugationUnconjugated

IsotypeIgG

ImmunogenFull length recombinant 14.3.3 protein ETA expressed in and purified from E. coli.

STJA0040760-100

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Short Description	Mouse monoclonal anti-14-3-3 protein eta (Full-Length) for use in ICC, IHC-F and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	ICC/IHC-F/WB
Host	Mouse
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	3G12
Isotype	IgG
Conjugation	Unconjugated
Purification	IgG
Dilution Range	WB 1:1000-1:5000 IHC 1:500-1:1000 ICC 1:500-1:1000
Formulation	Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide
Storage Instruction	Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. After reconstitution of lyophilized antibody, aliquot and store at-20°C for

Gene Symbol	YWHAH
Gene ID	7533
Uniprot ID	1433F_HUMAN
Immunogen	Full length recombinant 14.3.3 protein ETA expressed in and purified from E. coli.
Immunogen Region	Full-Length
Immunogen Sequence	Human
Specificity	Human 14-3-3 ETA protein.

Tissue Specificity	Expressed mainly in the brain and present in other tissues albeit at lower levels.
Post Translational Modifications	Phosphorylated on Ser-59 by protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion.
Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
Protein Name	14-3-3 Protein Eta Protein As1
Database Links	Reactome: R-HSA-111447 Reactome: R-HSA-1445148 Reactome: R-HSA-5625740 Reactome: R-HSA-5628897 Reactome: R-HSA-75035 Reactome: R-HSA-9735871 Reactome: R-HSA-9755779 Reactome: R-HSA-9856649
Cellular Localisation
Alternative Antibody Names	Anti-14-3-3 Protein Eta antibody Anti-Protein As1 antibody Anti-YWHAH antibody Anti-YWHA1 antibody

Information sourced from Uniprot.org