Primary Antibodies for Research Use
Polyclonal, monoclonal and recombinant antibodies for immunodetectionOur range covers polyclonal, monoclonal and recombinant primary antibodies for Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) and Flow Cytometry (FC). Antibodies are available in a range of pack sizes, including trial sizes, to suit different budgets and experimental scales.
Specialty antibody products
A few individual products worth knowing about, each solving a specific experimental need rather than covering a whole target category.
Rabbit IgG Isotype Control [S5763RM]
Matched host and isotype without target specificity, for separating real signal from background.
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Anti-GAPDH antibody [S3MM]
Stably expressed reference protein used to confirm equal loading across Western Blot lanes.
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Anti-GFP-Tag antibody [Mix]
Detects any GFP-fusion construct directly, without needing a target-specific antibody.
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Anti-CANX antibody (543-592 aa)
ER membrane chaperone, used as a standard marker for the endoplasmic reticulum in IF co-staining.
View product →Two targets researchers reach for first
Beta-actin is a structural protein used to confirm equal loading across every lane of a Western Blot. Ki-67 marks which cells in a tissue section are actively dividing. Both are among the most frequently ordered targets in the range.
Anti-ACTB antibody (1-80 aa) (STJ91464)
Beta-actin is a cytoskeletal protein expressed at stable levels across most cell types, which is why it is the default reference band for confirming equal protein loading in Western Blot. This rabbit polyclonal antibody reacts across a wide panel of species, from human and mouse through to chicken, cow and sheep, making it usable as a loading control across mixed-species experiments.
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Anti-Ki-67 antibody [ZR433] (STJ180649)
Ki-67 is expressed only in actively cycling cells and is absent from resting cells in G0, making it a standard marker for measuring the growth fraction of a tissue sample. This rabbit monoclonal is validated for IHC-P in human tissue, giving nuclear staining in proliferating cell populations such as lymphocytes in tonsil germinal centres.
View product →Primary antibodies by research area
A curated set of targets from across the catalogue, organised by the research field they are most often used in.
Neuroscience
Astrocyte and glial markers for identifying and characterising the non-neuronal cell populations of the central nervous system. GFAP is the standard marker for astrocyte identification and reactive gliosis, connexin-43 forms the gap junctions that electrically and metabolically couple astrocyte networks, and S100B is a calcium-binding protein highly expressed in astrocytes that also acts as a neurotrophic factor supporting astrocytosis and axonal growth.
Cancer Studies
Markers used to characterise tumour growth, invasion and the hypoxic tumour microenvironment. EGFR is a receptor tyrosine kinase overexpressed in several solid tumours, cyclins A and B1 mark distinct phases of the cell cycle, HIF1A accumulates under the low-oxygen conditions found in solid tumour cores, and MMP2 degrades extracellular matrix components during tissue invasion and metastasis.
Signal Transduction
Phospho-specific antibodies for tracking the activation state of core signalling cascades. ERK1/2 and JNK1/2/3 are MAPK-family kinases activated by phosphorylation at conserved threonine and tyrosine residues, Akt-Ser473 and GSK3B-Ser9 phosphorylation report on PI3K/Akt pathway activity, mTOR-Ser2448 reflects mTORC1 activation downstream of growth factor signalling, and PIK3CA is the catalytic subunit of PI3K itself.
Immunology
Targets involved in cytokine signalling and immune-mediated tissue remodelling. Phosphorylated NF-κB p65 marks active nuclear translocation of the NF-κB transcription factor complex, JAK1 sits immediately downstream of type I and type II cytokine receptors, SOCS1 provides negative feedback on cytokine-driven JAK/STAT signalling, TGFB1 is a regulatory cytokine with immunosuppressive and fibrotic roles, and TIMP1 balances matrix metalloproteinase activity during inflammatory tissue remodelling.
Looking for a Specific Target?
Our primary antibody range spans polyclonal, monoclonal and recombinant formats across tens of thousands of validated targets, with the specialty and research-area products above representing a small selection.
Browse all primary antibodies