Name: Human NKX2-5 protein (Recombinant) (N-GST & C-His) (STJP007746)
SKU: STJP007746
Availability: InStock

Human NKX2-5 protein (Recombinant) (N-GST & C-His) (STJP007746)

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STJP007746

$287.73 - $1,605.63

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Short Description :	Recombinant-Human NKX2-5-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Transcription factor required for the development of the heart and the spleen. During heart development, acts as a transcriptional activator of NPPA/ANF in cooperation with GATA4. May cooperate with TBX2 to negatively modulate expression of NPPA/ANF in the atrioventricular canal. Binds to the core DNA motif of NPPA promoter. Together with PBX1, required for spleen development through a mechanism that involves CDKN2B repression. Positively regulates transcription of genes such as COL3A1 and MMP2, resulting in increased pulmonary endothelial fibrosis in response to hypoxia.
Protein Name	Homeobox Protein Nkx-2.5 Cardiac-Specific Homeobox Homeobox Protein Csx Homeobox Protein Nk-2 Homolog E
Database Links	Reactome: R-HSA-2032785 Reactome: R-HSA-5578768 Reactome: R-HSA-9733709
Cellular Localisation	Nucleus
Alternative Protein Names	Homeobox Protein Nkx-2.5 protein Cardiac-Specific Homeobox protein Homeobox Protein Csx protein Homeobox Protein Nk-2 Homolog E protein NKX2-5 protein CSX protein NKX2.5 protein NKX2E protein

Information sourced from Uniprot.org

Human NKX2-5 protein (Recombinant) (N-GST & C-His) (STJP007746)

General Information

Model	Name	Host	Application
STJP015315	Human NKX2-6 protein (Recombinant) (N-GST & C-His) (STJP015315)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP011289	Human SOX9, N-GST & C-His protein (Recombinant) (N-GST & C-His) (STJP011289)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP004756	Human NKX2-1 protein (Recombinant) (N-GST) (STJP004756)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP009619	Human WAS protein (Recombinant) (N-GST & C-His) (STJP009619)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP008822	Human COX10 protein (Recombinant) (N-GST & C-His) (STJP008822)	E.coli	ELISA/Immunogen/SDS-PAGE/WB