Human Hepatocyte growth factor/HGF protein (Recombinant) (C-His) (STJP002813)

SKU:
STJP002813

Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Hepatocyte growth factor/HGF-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Measured by its ability to induce IL-11 secretion by Saos-2 human osteosarcoma cells. Hjertner, O. et al. (1999) Blood 94:3883. The ED50 for this effect is 2.23-8.91 ng/mL, corresponding to a specific activity of 1.12×105-4.48×105 units/mg.
Gene Symbol: HGF
Gene ID: 3082
Uniprot ID: HGF_HUMAN
Immunogen Region: Gln32-Ser728
Immunogen: Recombinant Human Hepatocyte growth factor/HGF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln32-Ser728) of human Hepatocyte growth factor/HGF (Accession #NP_000592.3) fused with and a 6×His t
Function Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation.
Protein Name Hepatocyte Growth Factor
Hepatopoietin-A
Scatter Factor
Sf Cleaved Into - Hepatocyte Growth Factor Alpha Chain - Hepatocyte Growth Factor Beta Chain
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-1257604
Reactome: R-HSA-1266695
Reactome: R-HSA-2219530
Reactome: R-HSA-5673001
Reactome: R-HSA-6785807
Reactome: R-HSA-6806942
Reactome: R-HSA-6807004
Reactome: R-HSA-6811558
Reactome: R-HSA-8851805
Reactome: R-HSA-8851907
Reactome: R-HSA-8865999
Reactome: R-HSA-8874081
Reactome: R-HSA-8875513
Reactome: R-HSA-8875555
Reactome: R-HSA-8875656
Reactome: R-HSA-8875791
Reactome: R-HSA-9734091
Alternative Protein Names Hepatocyte Growth Factor protein
Hepatopoietin-A protein
Scatter Factor protein
Sf Cleaved Into - Hepatocyte Growth Factor Alpha Chain - Hepatocyte Growth Factor Beta Chain protein
HGF protein
HPTA protein

Information sourced from Uniprot.org

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