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Human Hepatocyte growth factor/HGF protein (Recombinant) (C-His) (STJP002813)

Human Hepatocyte growth factor/HGF protein (Recombinant) (C-His) (STJP002813)

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STJP002813

$120.83 - $482.63

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General Information
Product Properties
Target Information
Additional Info
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Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	<0.1 EU/Mu g
Immunoreactivity:	Measured by its ability to induce IL-11 secretion by Saos-2 human osteosarcoma cells. Hjertner, O. et al. (1999) Blood 94:3883. The ED₅₀ for this effect is 2.23-8.91 ng/mL, corresponding to a specific activity of 1.12×10⁵-4.48×1

Gene Symbol:	HGF
Gene ID:	3082
Uniprot ID:	HGF_HUMAN
Immunogen Region:	Gln32-Ser728
Immunogen:	Recombinant Human Hepatocyte growth factor/HGF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln32-Ser728) of human Hepatocyte growth factor/HGF (Accession #NP_000592.3) fused with and a 6×His t
Immunogen Sequence:	QRKRRNTIHEFKKSAKTTLI KIDPALKIKTKKVNTADQCA NRCTRNKGLPFTCKAFVFDK ARKQCLWFPFNSMSSGVKKE FGHEFDLYENKDYIRNCIIG KGRSYKGTVSITKSGIKCQP WSSMIPHEHSFLPSSYRGKD LQENYCRNPRGEEGGPWCFT SNPEVRYEVCDIPQCSEVEC MTCNGESYRGLMDHTESGKI CQRWDHQTPHRHKFLPERYP DKGFDDNYCRNPDGQPRPW

Function	Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation.
Protein Name	Hepatocyte Growth Factor Hepatopoietin-A Scatter Factor Sf Cleaved Into - Hepatocyte Growth Factor Alpha Chain - Hepatocyte Growth Factor Beta Chain
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-1257604 Reactome: R-HSA-1266695 Reactome: R-HSA-2219530 Reactome: R-HSA-5673001 Reactome: R-HSA-6785807 Reactome: R-HSA-6806942 Reactome: R-HSA-6807004 Reactome: R-HSA-6811558 Reactome: R-HSA-8851805 Reactome: R-HSA-8851907 Reactome: R-HSA-8865999 Reactome: R-HSA-8874081 Reactome: R-HSA-8875513 Reactome: R-HSA-8875555 Reactome: R-HSA-8875656 Reactome: R-HSA-8875791 Reactome: R-HSA-9734091
Alternative Protein Names	Hepatocyte Growth Factor protein Hepatopoietin-A protein Scatter Factor protein Sf Cleaved Into - Hepatocyte Growth Factor Alpha Chain - Hepatocyte Growth Factor Beta Chain protein HGF protein HPTA protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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