Human GOLM1 protein (Recombinant) (His-Tag) (STJP018530)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GOLM1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GOLM1 |
| Gene ID | 51280 |
| Uniprot ID | GOLM1_HUMAN |
| Accession Number | NP_808800 |
| Immunogen | Human |
| Immunogen Region | 36-401aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSSSRSVDL QTRIMELEGR VRRAAAERGA VELKKNEFQG ELEKQREQLD KIQSSHNFQL ESVNKLYQDE KAVLVNNITT GERLIRVLQD QLKTLQRNYG RLQQDVLQFQ KNQTNLERKF SYDLSQCINQ MKEVKEQCEE RIEEVTKKGN EAVASRDLSE NNDQRQQLQA LSEPQPRLQA AGLPHTEVPQ GKGNVLGNSK SQTPAPSS |
Additional Info
| Tissue Specificity | Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes. |
| Post Translational Modifications | Glycosylated. Phosphorylation sites are present in the extracellular medium. |
| Function | Unknown. Cellular response protein to viral infection. |
| Protein Name | Golgi Membrane Protein 1Golgi Membrane Protein Gp73Golgi Phosphoprotein 2 |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Golgi ApparatusCis-Golgi Network MembraneSingle-Pass Type Ii Membrane ProteinEarly GolgiCycles Via The Cell Surface And Endosomes Upon Lumenal Ph Disruption |
| Alternative Protein Names | Golgi Membrane Protein 1 proteinGolgi Membrane Protein Gp73 proteinGolgi Phosphoprotein 2 proteinGOLM1 proteinC9orf155 proteinGOLPH2 proteinPSEC0242 proteinUNQ686 proteinPRO1326 protein |
Information sourced from Uniprot.org