| Tissue Specificity | Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes. |
| Post Translational Modifications | Glycosylated. Phosphorylation sites are present in the extracellular medium. |
| Function | Unknown. Cellular response protein to viral infection. |
| Protein Name | Golgi Membrane Protein 1Golgi Membrane Protein Gp73Golgi Phosphoprotein 2 |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Golgi ApparatusCis-Golgi Network MembraneSingle-Pass Type Ii Membrane ProteinEarly GolgiCycles Via The Cell Surface And Endosomes Upon Lumenal Ph Disruption |
| Alternative Protein Names | Golgi Membrane Protein 1 proteinGolgi Membrane Protein Gp73 proteinGolgi Phosphoprotein 2 proteinGOLM1 proteinC9orf155 proteinGOLPH2 proteinPSEC0242 proteinUNQ686 proteinPRO1326 protein |
Information sourced from Uniprot.org