Human GOLM1 protein (Recombinant) (His-Tag) (STJP018530)

SKU:
STJP018530
£134.50 - £738.50
Processing The item has been added

Short Description :Recombinant-Human GOLM1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:GOLM1
Gene ID:51280
Uniprot ID:GOLM1_HUMAN
Accession Number:NP_808800
Immunogen:Human
Immunogen Region:36-401aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MGSSSRSVDL QTRIMELEGR VRRAAAERGA VELKKNEFQG ELEKQREQLD KIQSSHNFQL ESVNKLYQDE KAVLVNNITT GERLIRVLQD QLKTLQRNYG RLQQDVLQFQ KNQTNLERKF SYDLSQCINQ MKEVKEQCEE RIEEVTKKGN EAVASRDLSE NNDQRQQLQA LSEPQPRLQA AGLPHTEVPQ GKGNVLGNSK SQTPAPSS
Tissue Specificity Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes.
Post Translational Modifications Glycosylated. Phosphorylation sites are present in the extracellular medium.
Function Unknown. Cellular response protein to viral infection.
Protein Name Golgi Membrane Protein 1
Golgi Membrane Protein Gp73
Golgi Phosphoprotein 2
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Golgi Apparatus
Cis-Golgi Network Membrane
Single-Pass Type Ii Membrane Protein
Early Golgi
Cycles Via The Cell Surface And Endosomes Upon Lumenal Ph Disruption
Alternative Protein Names Golgi Membrane Protein 1 protein
Golgi Membrane Protein Gp73 protein
Golgi Phosphoprotein 2 protein
GOLM1 protein
C9orf155 protein
GOLPH2 protein
PSEC0242 protein
UNQ686 protein
PRO1326 protein

Information sourced from Uniprot.org