SDS-PAGE gel of recombinant human FIS1 protein under reducing conditions Coomassie blue stain

Human FIS1 protein (Recombinant) (His-Tag) (STJP016702)

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STJP016702
£125.50 - £649.50
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Short Description :Recombinant-Human FIS1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:FIS1
Gene ID:51024
Uniprot ID:FIS1_HUMAN
Accession Number:NP_057152
Immunogen:Human
Immunogen Region:1-122aa
Immunogen Sequence: MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK DG
Post Translational Modifications Ubiquitinated by MARCHF5.
Function Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. May not be essential for the assembly of functional fission complexes and the subsequent membrane scission event. Also mediates peroxisomal fission. May act when the products of fission are directed toward mitochondrial homeostasis, mitophagy, or apoptosis. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis.
Protein Name Mitochondrial Fission 1 Protein
Fis1 Homolog
Hfis1
Tetratricopeptide Repeat Protein 11
Tpr Repeat Protein 11
Database Links Reactome: R-HSA-9603798
Cellular Localisation Mitochondrion Outer Membrane
Single-Pass Membrane Protein
Peroxisome Membrane
Alternative Protein Names Mitochondrial Fission 1 Protein protein
Fis1 Homolog protein
Hfis1 protein
Tetratricopeptide Repeat Protein 11 protein
Tpr Repeat Protein 11 protein
FIS1 protein
TTC11 protein
CGI-135 protein

Information sourced from Uniprot.org

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