Name: Human DROSHA protein (Recombinant) (N-GST) (STJP006081)
SKU: STJP006081
Availability: InStock

Human DROSHA protein (Recombinant) (N-GST) (STJP006081)

SKU:

STJP006081

$287.73 - $1,605.63

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Short Description :	Recombinant-Human DROSHA-N-GST protein was developed from e.coli for the region N-GST. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	Degraded by autophagy in response to neuronal activity in motor neurons.
Function	Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies. Plays a role in growth homeostasis in response to autophagy in motor neurons.
Protein Name	Ribonuclease 3 Protein Drosha Ribonuclease Iii Rnase Iii P241
Database Links	Reactome: R-HSA-203927
Cellular Localisation	Nucleus Nucleolus Cytoplasm A Fraction Is Translocated To The Nucleolus During The S Phase Of The Cell Cycle Localized In Gw Bodies (Gwbs) Also Known As P-Bodies
Alternative Protein Names	Ribonuclease 3 protein Protein Drosha protein Ribonuclease Iii protein Rnase Iii protein P241 protein DROSHA protein RN3 protein RNASE3L protein RNASEN protein

Information sourced from Uniprot.org

Human DROSHA protein (Recombinant) (N-GST) (STJP006081)

General Information

Model	Name	Host	Application
STJP005387	Human TFDP1 protein (Recombinant) (N-GST) (STJP005387)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP005868	Human SLC26A8 protein (Recombinant) (N-GST) (STJP005868)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP005851	Human TAFA4 protein (Recombinant) (N-GST) (STJP005851)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP006239	Human INVS protein (Recombinant) (N-GST) (STJP006239)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP006084	Human GKN1 protein (Recombinant) (N-GST) (STJP006084)	E.coli	ELISA/Immunogen/SDS-PAGE/WB