SDS-PAGE gel of recombinant human ASPRV1 protein 3µg under reducing conditions Coomassie blue stain

Human ASPRV1 protein (Recombinant) (His-Tag) (STJP017876)

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STJP017876
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Short Description :Recombinant-Human ASPRV1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.25 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:ASPRV1
Gene ID:151516
Uniprot ID:APRV1_HUMAN
Accession Number:NP_690005
Immunogen:Human
Immunogen Region:191-326aa
Immunogen Sequence:SMGKGYY LKGKIGKVPV RFLVDSGAQV SVVHPNLWEE VTDGDLDTLQ PFENVVKVAN GAEMKILGVW DTAVSLGKLK LKAQFLVANA SAEEAIIGTD VLQDHNAILD FEHRTCTLKG KKFRLLPVGG SLEDEFDLE
Tissue Specificity Expressed primarily in the granular layer of the epidermis and inner root sheath of hair follicles. In psoriatic skin, expressed throughout the stratum corneum. In ulcerated skin, expressed in the stratum granulosum of intact epidermis but almost absent from ulcerated regions. Expressed in differentiated areas of squamous cell carcinomas but not in undifferentiated tumors.
Post Translational Modifications Undergoes autocleavage which is necessary for activation of the protein.
Function Protease responsible for filaggrin processing, essential for the maintenance of a proper epidermis organization.
Protein Name Retroviral-Like Aspartic Protease 1
Skin-Specific Retroviral-Like Aspartic Protease
Saspase
Skin Aspartic Protease
Tpa-Inducible Aspartic Proteinase-Like Protein
Taps
Database Links
Cellular Localisation Membrane
Single-Pass Membrane Protein
Alternative Protein Names Retroviral-Like Aspartic Protease 1 protein
Skin-Specific Retroviral-Like Aspartic Protease protein
Saspase protein
Skin Aspartic Protease protein
Tpa-Inducible Aspartic Proteinase-Like Protein protein
Taps protein
ASPRV1 protein
SASP protein

Information sourced from Uniprot.org

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