Human APLP2 protein (Recombinant) (N-His) (STJP005200)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human APLP2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | APLP2 |
| Gene ID | 334 |
| Uniprot ID | APLP2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Gly210 |
Additional Info
| Post Translational Modifications | The BPTI/Kunitz inhibitor domain is O-glycosylated. |
| Function | May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts. |
| Protein Name | Amyloid Beta Precursor Like Protein 2ApphAmyloid BetaA4 Precursor-Like Protein 2Amyloid Protein HomologAmyloid-Like Protein 2Aplp-2Cdei Box-Binding ProteinCdebpSperm Membrane Protein Ywk-Ii |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinNucleus |
| Alternative Protein Names | Amyloid Beta Precursor Like Protein 2 proteinApph proteinAmyloid Beta proteinA4 Precursor-Like Protein 2 proteinAmyloid Protein Homolog proteinAmyloid-Like Protein 2 proteinAplp-2 proteinCdei Box-Binding Protein proteinCdebp proteinSperm Membrane Protein Ywk-Ii proteinAPLP2 proteinAPPL2 protein |
Information sourced from Uniprot.org