Human APLP2 protein (Recombinant) (N-His) (STJP005200)

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STJP005200
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human APLP2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: APLP2
Gene ID: 334
Uniprot ID: APLP2_HUMAN
Immunogen Region: Met1-Gly210
Immunogen: Homo sapiens (Human)
Post Translational Modifications The BPTI/Kunitz inhibitor domain is O-glycosylated.
Function May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts.
Protein Name Amyloid Beta Precursor Like Protein 2
Apph
Amyloid Beta
A4 Precursor-Like Protein 2
Amyloid Protein Homolog
Amyloid-Like Protein 2
Aplp-2
Cdei Box-Binding Protein
Cdebp
Sperm Membrane Protein Ywk-Ii
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Nucleus
Alternative Protein Names Amyloid Beta Precursor Like Protein 2 protein
Apph protein
Amyloid Beta protein
A4 Precursor-Like Protein 2 protein
Amyloid Protein Homolog protein
Amyloid-Like Protein 2 protein
Aplp-2 protein
Cdei Box-Binding Protein protein
Cdebp protein
Sperm Membrane Protein Ywk-Ii protein
APLP2 protein
APPL2 protein

Information sourced from Uniprot.org