Post Translational Modifications | The BPTI/Kunitz inhibitor domain is O-glycosylated. |
Function | May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts. |
Protein Name | Amyloid Beta Precursor Like Protein 2ApphAmyloid BetaA4 Precursor-Like Protein 2Amyloid Protein HomologAmyloid-Like Protein 2Aplp-2Cdei Box-Binding ProteinCdebpSperm Membrane Protein Ywk-Ii |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinNucleus |
Alternative Protein Names | Amyloid Beta Precursor Like Protein 2 proteinApph proteinAmyloid Beta proteinA4 Precursor-Like Protein 2 proteinAmyloid Protein Homolog proteinAmyloid-Like Protein 2 proteinAplp-2 proteinCdei Box-Binding Protein proteinCdebp proteinSperm Membrane Protein Ywk-Ii proteinAPLP2 proteinAPPL2 protein |
Information sourced from Uniprot.org