| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TRIAP1 (1-76) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRIAP1 |
| Gene ID: |
51499 |
| Uniprot ID: |
TRIA1_HUMAN |
| Immunogen Region: |
1-76 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human TRIAP1 (NP_057483.1). |
| Immunogen Sequence: |
MNSVGEACTDMKREYDQCFN RWFAEKFLKGDSSGDPCTDL FKRYQQCVQKAIKEKEIPIE GLEFMGHGKEKPENSS |
| Function | Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis. |
| Protein Name | Tp53-Regulated Inhibitor Of Apoptosis 1Protein 15e1.1Wf-1P53-Inducible Cell-Survival FactorP53csv |
| Database Links | Reactome: R-HSA-6803204 |
| Cellular Localisation | MitochondrionMitochondrion Intermembrane Space |
| Alternative Antibody Names | Anti-Tp53-Regulated Inhibitor Of Apoptosis 1 antibodyAnti-Protein 15e1.1 antibodyAnti-Wf-1 antibodyAnti-P53-Inducible Cell-Survival Factor antibodyAnti-P53csv antibodyAnti-TRIAP1 antibodyAnti-15E1.1 antibodyAnti-HSPC132 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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