Anti-TRIAP1 antibody (1-76) (STJ29452)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TRIAP1 (1-76) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRIAP1 |
| Gene ID | 51499 |
| Uniprot ID | TRIA1_HUMAN |
| Immunogen Region | 1-76 |
| Immunogen Sequence | MNSVGEACTDMKREYDQCFN RWFAEKFLKGDSSGDPCTDL FKRYQQCVQKAIKEKEIPIE GLEFMGHGKEKPENSS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human TRIAP1 (NP_057483.1). |
Additional Info
| Function | Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis. |
| Protein Name | Tp53-Regulated Inhibitor Of Apoptosis 1Protein 15e1.1Wf-1P53-Inducible Cell-Survival FactorP53csv |
| Database Links | Reactome: R-HSA-6803204Reactome: R-HSA-9837999 |
| Cellular Localisation | MitochondrionMitochondrion Intermembrane Space |
| Alternative Antibody Names | Anti-Tp53-Regulated Inhibitor Of Apoptosis 1 antibodyAnti-Protein 15e1.1 antibodyAnti-Wf-1 antibodyAnti-P53-Inducible Cell-Survival Factor antibodyAnti-P53csv antibodyAnti-TRIAP1 antibodyAnti-15E1.1 antibodyAnti-HSPC132 antibody |
Information sourced from Uniprot.org