| Function | Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis. |
| Protein Name | Tp53-Regulated Inhibitor Of Apoptosis 1Protein 15e1.1Wf-1P53-Inducible Cell-Survival FactorP53csv |
| Database Links | Reactome: R-HSA-6803204Reactome: R-HSA-9837999 |
| Cellular Localisation | MitochondrionMitochondrion Intermembrane Space |
| Alternative Antibody Names | Anti-Tp53-Regulated Inhibitor Of Apoptosis 1 antibodyAnti-Protein 15e1.1 antibodyAnti-Wf-1 antibodyAnti-P53-Inducible Cell-Survival Factor antibodyAnti-P53csv antibodyAnti-TRIAP1 antibodyAnti-15E1.1 antibodyAnti-HSPC132 antibody |
Information sourced from Uniprot.org
