| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim44 (10-240) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4197RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TIMM44 |
| Gene ID: |
10469 |
| Uniprot ID: |
TIM44_HUMAN |
| Immunogen Region: |
10-240 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 10-240 of human TIM44 (NP_006342.2). |
| Immunogen Sequence: |
WCRCPRRCLGSGIQFLSSHN LPHGSTYQMRRPGGELPLSK SYSSGNRKGFLSGLLDNVKQ ELAKNKEMKESIKKFRDEAR RLEESDVLQEARRKYKTIES ETVRTSEVLRKKLGELTGTV KESLHEVSKSDLGRKIKEGV EEAAKTAKQSAESVSKGGEK LGRTAAFRALSQGVESVKKE IDDSVLGQTGPYRRPQRLRK RTEFAGDKFKEEKVFEPNEE ALGVVLHKDSK |
| Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim44 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix SideMitochondrion Matrix |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim44 antibodyAnti-TIMM44 antibodyAnti-MIMT44 antibodyAnti-TIM44 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
