Anti-TIMM44 antibody (10-240) [S4197RM] (STJ11104197)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Mitochondrial Import Inner Membrane Translocase Subunit Tim44 (10-240) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4197RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TIMM44 |
| Gene ID | 10469 |
| Uniprot ID | TIM44_HUMAN |
| Immunogen Region | 10-240 |
| Immunogen Sequence | WCRCPRRCLGSGIQFLSSHN LPHGSTYQMRRPGGELPLSK SYSSGNRKGFLSGLLDNVKQ ELAKNKEMKESIKKFRDEAR RLEESDVLQEARRKYKTIES ETVRTSEVLRKKLGELTGTV KESLHEVSKSDLGRKIKEGV EEAAKTAKQSAESVSKGGEK LGRTAAFRALSQGVESVKKE IDDSVLGQTGPYRRPQRLRK RTEFAGDKFKEEKVFEPNEE ALGVVLHKDSK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 10-240 of human TIM44 (NP_006342.2). |
Additional Info
| Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim44 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix SideMitochondrion Matrix |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim44 antibodyAnti-TIMM44 antibodyAnti-MIMT44 antibodyAnti-TIM44 antibody |
Information sourced from Uniprot.org