Anti-THUMPD3 antibody (1-250) (STJ112442)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal THUMPD3 (1-250) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | THUMPD3 |
| Gene ID | 25917 |
| Uniprot ID | THUM3_HUMAN |
| Immunogen Region | 1-250 |
| Immunogen Sequence | MCDIEEATNQLLDVNLHENQ KSVQVTESDLGSESELLVTI GATVPTGFEQTAADEVREKL GSSCKISRDRGKIYFVISVE SLAQVHCLRSVDNLFVVVQE FQDYQFKQTKEEVLKDFEDL AGKLPWSNPLKVWKINASFK KKKAKRKKINQNSSKEKINN GQEVKIDQRNVKKEFTSHAL DSHILDYYENPAIKEDVSTL IGDDLASCKDETDESSKEET EPQVLKFRVTCNRAGEKHC |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human THUMPD3 (NP_056268.2). |
Additional Info
| Function | Catalytic subunit of the THUMPD3-TRM112 methyltransferase complex, that specifically mediates the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 6 (m2G6) in tRNAs. This is one of the major tRNA (guanine-N(2))-methyltransferases. Also catalyzes the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 7 of tRNA(Trp). |
| Protein Name | TrnaGuanine(6-N(2-Methyltransferase Thump3Thump Domain-Containing Protein 3Trna(TrpGuanine(7-N(2-Methyltransferase Thump3 |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Trna antibodyAnti-Guanine(6-N(2-Methyltransferase Thump3 antibodyAnti-Thump Domain-Containing Protein 3 antibodyAnti-Trna(Trp antibodyAnti-Guanine(7-N(2-Methyltransferase Thump3 antibodyAnti-THUMPD3 antibody |
Information sourced from Uniprot.org