Anti-SODD antibody (Internal) (STJ71776)

SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
STJ71776-100
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General Information

Short DescriptionGoat polyclonal antibody anti-SODD (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
ApplicationsPep-ELISA/WB/IHC
HostGoat
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:8000.
WB: Approx. 60kDa band observed in cell lines HEK293 and HeLa lysates (calculated MW of 49.6kDa according to NP_004865.1). The observed molecular weight corresponds to earlier findings in l
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20°C on receipt and minimise freeze-thaw cycles.

Target Information

Gene SymbolBAG4
Gene ID9530
Uniprot IDBAG4_HUMAN
Accession NumberNP_004865.1
Immunogen RegionInternal
Immunogen SequenceGNATSDHPNNQDQSS

Additional Info

Function Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria.
Protein Name Bag Family Molecular Chaperone Regulator 4
Bag-4
Bcl-2-Associated Athanogene 4
Silencer Of Death Domains
Database Links Reactome: R-HSA-3371453
Reactome: R-HSA-5655302
Reactome: R-HSA-75893
Reactome: R-HSA-8853336
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Bag Family Molecular Chaperone Regulator 4 antibody
Anti-Bag-4 antibody
Anti-Bcl-2-Associated Athanogene 4 antibody
Anti-Silencer Of Death Domains antibody
Anti-BAG4 antibody
Anti-SODD antibody

Information sourced from Uniprot.org

Citations

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