| Short Description : | Goat polyclonal antibody anti-SODD (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications: | Pep-ELISA/WB/IHC |
| Host: | Goat |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx. 60kDa band observed in cell lines HEK293 and HeLa lysates (calculated MW of 49.6kDa according to NP_004865.1). The observed molecular weight corresponds to earlier findings in l |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | BAG4 |
| Gene ID: | 9530 |
| Uniprot ID: | BAG4_HUMAN |
| Accession Number: | NP_004865.1 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | GNATSDHPNNQDQSS |
| Function | Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria. |
| Protein Name | Bag Family Molecular Chaperone Regulator 4Bag-4Bcl-2-Associated Athanogene 4Silencer Of Death Domains |
| Database Links | Reactome: R-HSA-3371453Reactome: R-HSA-5655302Reactome: R-HSA-75893Reactome: R-HSA-8853336 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Bag Family Molecular Chaperone Regulator 4 antibodyAnti-Bag-4 antibodyAnti-Bcl-2-Associated Athanogene 4 antibodyAnti-Silencer Of Death Domains antibodyAnti-BAG4 antibodyAnti-SODD antibody |
Information sourced from Uniprot.org
