Anti-SMU1 antibody (1-220) (STJ111571)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SMU1 (1-220) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SMU1 |
| Gene ID | 55234 |
| Uniprot ID | SMU1_HUMAN |
| Immunogen Region | 1-220 |
| Immunogen Sequence | MSIEIESSDVIRLIMQYLKE NSLHRALATLQEETTVSLNT VDSIESFVADINSGHWDTVL QAIQSLKLPDKTLIDLYEQV VLELIELRELGAARSLLRQT DPMIMLKQTQPERYIHLENL LARSYFDPREAYPDGSSKEK RRAAIAQALAGEVSVVPPSR LMALLGQALKWQQHQGLLPP GMTIDLFRGKAAVKDVEEEK FPTQLSRHIKFGQKSHVECA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SMU1 (NP_060695.2). |
Additional Info
| Function | Involved in pre-mRNA splicing as a component of the spliceosome. Regulates alternative splicing of the HSPG2 pre-mRNA. Required for normal accumulation of IK. Required for normal mitotic spindle assembly and normal progress through mitosis. (Microbial infection) Required, together with IK, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles. |
| Protein Name | Wd40 Repeat-Containing Protein Smu1Smu-1 Suppressor Of Mec-8 And Unc-52 Protein Homolog Cleaved Into - Wd40 Repeat-Containing Protein Smu1 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | CytoplasmNucleusNucleus SpeckleColocalizes With Srsf1 In Nuclear Speckles |
| Alternative Antibody Names | Anti-Wd40 Repeat-Containing Protein Smu1 antibodyAnti-Smu-1 Suppressor Of Mec-8 And Unc-52 Protein Homolog Cleaved Into - Wd40 Repeat-Containing Protein Smu1 - N-Terminally Processed antibodyAnti-SMU1 antibody |
Information sourced from Uniprot.org