| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SMU1 (1-220) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SMU1 |
| Gene ID: |
55234 |
| Uniprot ID: |
SMU1_HUMAN |
| Immunogen Region: |
1-220 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SMU1 (NP_060695.2). |
| Immunogen Sequence: |
MSIEIESSDVIRLIMQYLKE NSLHRALATLQEETTVSLNT VDSIESFVADINSGHWDTVL QAIQSLKLPDKTLIDLYEQV VLELIELRELGAARSLLRQT DPMIMLKQTQPERYIHLENL LARSYFDPREAYPDGSSKEK RRAAIAQALAGEVSVVPPSR LMALLGQALKWQQHQGLLPP GMTIDLFRGKAAVKDVEEEK FPTQLSRHIKFGQKSHVECA |
| Function | Involved in pre-mRNA splicing as a component of the spliceosome. Regulates alternative splicing of the HSPG2 pre-mRNA. Required for normal accumulation of IK. Required for normal mitotic spindle assembly and normal progress through mitosis. (Microbial infection) Required, together with IK, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles. |
| Protein Name | Wd40 Repeat-Containing Protein Smu1Smu-1 Suppressor Of Mec-8 And Unc-52 Protein Homolog Cleaved Into - Wd40 Repeat-Containing Protein Smu1 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | CytoplasmNucleusNucleus SpeckleColocalizes With Srsf1 In Nuclear Speckles |
| Alternative Antibody Names | Anti-Wd40 Repeat-Containing Protein Smu1 antibodyAnti-Smu-1 Suppressor Of Mec-8 And Unc-52 Protein Homolog Cleaved Into - Wd40 Repeat-Containing Protein Smu1 - N-Terminally Processed antibodyAnti-SMU1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and Emerin/Emerin/EMD knockout (KO) 293T cells, using [KO Validated] Emerin/EMD Rabbit polyclonal antibody (STJ119989) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98774/382822/STJ119989_1__22320.1713151321.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and Emerin/Emerin/EMD knockout (KO) 293T cells, using [KO Validated] Emerin/EMD Rabbit polyclonal antibody (STJ119989) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")