| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SMU1 |
| Gene ID: | 55234 |
| Uniprot ID: | SMU1_HUMAN |
| Immunogen Region: | 1-220 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SMU1 (NP_060695.2). |
| Immunogen Sequence: | MSIEIESSDVIRLIMQYLKE NSLHRALATLQEETTVSLNT VDSIESFVADINSGHWDTVL QAIQSLKLPDKTLIDLYEQV VLELIELRELGAARSLLRQT DPMIMLKQTQPERYIHLENL LARSYFDPREAYPDGSSKEK RRAAIAQALAGEVSVVPPSR LMALLGQALKWQQHQGLLPP GMTIDLFRGKAAVKDVEEEK FPTQLSRHIKFGQKSHVECA |
| Function | Involved in pre-mRNA splicing as a component of the spliceosome. Regulates alternative splicing of the HSPG2 pre-mRNA. Required for normal accumulation of IK. Required for normal mitotic spindle assembly and normal progress through mitosis. (Microbial infection) Required, together with IK, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles. |
| Protein Name | Wd40 Repeat-Containing Protein Smu1Smu-1 Suppressor Of Mec-8 And Unc-52 Protein Homolog Cleaved Into - Wd40 Repeat-Containing Protein Smu1 - N-Terminally Processed |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | CytoplasmNucleusNucleus SpeckleColocalizes With Srsf1 In Nuclear Speckles |
| Alternative Antibody Names | Anti-Wd40 Repeat-Containing Protein Smu1 antibodyAnti-Smu-1 Suppressor Of Mec-8 And Unc-52 Protein Homolog Cleaved Into - Wd40 Repeat-Containing Protein Smu1 - N-Terminally Processed antibodyAnti-SMU1 antibody |
Information sourced from Uniprot.org
