Anti-SERPINF2 antibody (302-491) (STJ115978)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SERPINF2 (302-491) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINF2 |
| Gene ID | 5345 |
| Uniprot ID | A2AP_HUMAN |
| Immunogen Region | 302-491 |
| Immunogen Sequence | VPTHFEWNVSQVLANLSWDT LHPPLVWERPTKVRLPKLYL KHQMDLVATLSQLGLQELFQ APDLRGISEQSLVVSGVQHQ STLELSEVGVEAAAATSIAM SRMSLSSFSVNRPFLFFIFE DTTGLPLFVGSVRNPNPSAP RELKEQQDSPGNKDFLQSLK GFPRGDKLFGPDLKLVPPME EDYPQFGSPK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 302-491 of human SERPINF2 (NP_001159392.1). |
Additional Info
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | Proteolytically cleaved at Pro-39 by both the prolyl endopeptidase FAP form and antiplasmin-cleaving enzyme FAP soluble form to generate mature alpha-2-antiplasmin. |
| Function | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. |
| Protein Name | Alpha-2-AntiplasminAlpha-2-ApAlpha-2-Plasmin InhibitorAlpha-2-PiSerpin F2 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-75205 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-2-Antiplasmin antibodyAnti-Alpha-2-Ap antibodyAnti-Alpha-2-Plasmin Inhibitor antibodyAnti-Alpha-2-Pi antibodyAnti-Serpin F2 antibodyAnti-SERPINF2 antibodyAnti-AAP antibodyAnti-PLI antibody |
Information sourced from Uniprot.org