| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SERPINF2 (302-491) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SERPINF2 |
| Gene ID: |
5345 |
| Uniprot ID: |
A2AP_HUMAN |
| Immunogen Region: |
302-491 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 302-491 of human SERPINF2 (NP_001159392.1). |
| Immunogen Sequence: |
VPTHFEWNVSQVLANLSWDT LHPPLVWERPTKVRLPKLYL KHQMDLVATLSQLGLQELFQ APDLRGISEQSLVVSGVQHQ STLELSEVGVEAAAATSIAM SRMSLSSFSVNRPFLFFIFE DTTGLPLFVGSVRNPNPSAP RELKEQQDSPGNKDFLQSLK GFPRGDKLFGPDLKLVPPME EDYPQFGSPK |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | Proteolytically cleaved at Pro-39 by both the prolyl endopeptidase FAP form and antiplasmin-cleaving enzyme FAP soluble form to generate mature alpha-2-antiplasmin. |
| Function | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. |
| Protein Name | Alpha-2-AntiplasminAlpha-2-ApAlpha-2-Plasmin InhibitorAlpha-2-PiSerpin F2 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-75205 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-2-Antiplasmin antibodyAnti-Alpha-2-Ap antibodyAnti-Alpha-2-Plasmin Inhibitor antibodyAnti-Alpha-2-Pi antibodyAnti-Serpin F2 antibodyAnti-SERPINF2 antibodyAnti-AAP antibodyAnti-PLI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
