Host: |
Rabbit |
Applications: |
IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Sec14-Like Protein 2 (1-275) is suitable for use in Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SEC14L2 |
Gene ID: |
23541 |
Uniprot ID: |
S14L2_HUMAN |
Immunogen Region: |
1-275 |
Immunogen: |
Recombinant Protein corresponding to a sequence within amino acids 1-275 of human SEC14L2 (NP_203740.1). |
Immunogen Sequence: |
MSGRVGDLSPRQKEALAKFR ENVQDVLPALPNPDDYFLLR WLRARSFDLQKSEAMLRKHV EFRKQKDIDNIISWQPPEVI QQYLSGGMCGYDLDGCPVWY DIIGPLDAKGLLFSASKQDL LRTKMRECELLLQECAHQTT KLGRKVETITIIYDCEGLGL KHLWKPAVEAYGEFLCMFEE NYPETLKRLFVVKAPKLFPV AYNLIKPFLSEDTRKKIMVL GANWKEVLLKHISPDQVPV |
Tissue Specificity | Widely expressed. Strong expression in liver, brain and prostate. |
Function | Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell. |
Protein Name | Sec14-Like Protein 2Alpha-Tocopherol-Associated ProteinTapHtapSqualene Transfer ProteinSupernatant Protein FactorSpf |
Cellular Localisation | CytoplasmNucleusCytoplasmic In Absence Of Alpha-TocopherolAnd Nuclear In Presence Of Alpha-Tocopherol |
Alternative Antibody Names | Anti-Sec14-Like Protein 2 antibodyAnti-Alpha-Tocopherol-Associated Protein antibodyAnti-Tap antibodyAnti-Htap antibodyAnti-Squalene Transfer Protein antibodyAnti-Supernatant Protein Factor antibodyAnti-Spf antibodyAnti-SEC14L2 antibodyAnti-C22orf6 antibodyAnti-KIAA1186 antibodyAnti-KIAA1658 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance