Anti-SEC14L2 antibody (1-275) (STJ11105363)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Sec14-Like Protein 2 (1-275) antibody for use in IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SEC14L2 |
| Gene ID | 23541 |
| Uniprot ID | S14L2_HUMAN |
| Immunogen Region | 1-275 |
| Immunogen Sequence | MSGRVGDLSPRQKEALAKFR ENVQDVLPALPNPDDYFLLR WLRARSFDLQKSEAMLRKHV EFRKQKDIDNIISWQPPEVI QQYLSGGMCGYDLDGCPVWY DIIGPLDAKGLLFSASKQDL LRTKMRECELLLQECAHQTT KLGRKVETITIIYDCEGLGL KHLWKPAVEAYGEFLCMFEE NYPETLKRLFVVKAPKLFPV AYNLIKPFLSEDTRKKIMVL GANWKEVLLKHISPDQVPV |
| Specificity | Recombinant Protein corresponding to a sequence within amino acids 1-275 of human SEC14L2 (NP_203740.1). |
Additional Info
| Tissue Specificity | Widely expressed. Strong expression in liver, brain and prostate. |
| Function | Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell. |
| Protein Name | Sec14-Like Protein 2Alpha-Tocopherol-Associated ProteinTapHtapSqualene Transfer ProteinSupernatant Protein FactorSpf |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusCytoplasmic In Absence Of Alpha-TocopherolAnd Nuclear In Presence Of Alpha-Tocopherol |
| Alternative Antibody Names | Anti-Sec14-Like Protein 2 antibodyAnti-Alpha-Tocopherol-Associated Protein antibodyAnti-Tap antibodyAnti-Htap antibodyAnti-Squalene Transfer Protein antibodyAnti-Supernatant Protein Factor antibodyAnti-Spf antibodyAnti-SEC14L2 antibodyAnti-C22orf6 antibodyAnti-KIAA1186 antibodyAnti-KIAA1658 antibody |
Information sourced from Uniprot.org