• A) : STJ72757 (0. 5µg/ml) staining of HEK293 lysates overexpressing several HA-tagged Mouse GTPases, including Rrad (10µg protein in RIPA buffer) and compared with an HA-specific antibody. B) : STJ72757 (0. 5µg/ml) staining of WT and KO lysates of Mouse Heart (100µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-RRAD antibody (36-48) (STJ72757)

SKU:
STJ72757-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-RRAD (36-48) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:64000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: RRAD
Gene ID: 6236
Uniprot ID: RAD_HUMAN
Immunogen Region: 36-48
Accession Number: NP_004156.1
Specificity: Reported variants represent identical protein: NP_004156.1, NP_001122322.1
Immunogen Sequence: HRRSMPVDERDLQ
Function May regulate basal voltage-dependent L-type Ca(2+) currents and be required for beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.
Protein Name Gtp-Binding Protein Rad
Rad1
Ras Associated With Diabetes
Database Links Reactome: R-HSA-9031628
Cellular Localisation Cell Membrane
Alternative Antibody Names Anti-Gtp-Binding Protein Rad antibody
Anti-Rad1 antibody
Anti-Ras Associated With Diabetes antibody
Anti-RRAD antibody
Anti-RAD antibody

Information sourced from Uniprot.org

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