| Host: |
Rabbit |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RNF149 (221-400) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RNF149 |
| Gene ID: |
284996 |
| Uniprot ID: |
RN149_HUMAN |
| Immunogen Region: |
221-400 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 221-400 of human RNF149 (NP_775918.2). |
| Immunogen Sequence: |
FYYIQRFLYTGSQIGSQSHR KETKKVIGQLLLHTVKHGEK GIDVDAENCAVCIENFKVKD IIRILPCKHIFHRICIDPWL LDHRTCPMCKLDVIKALGYW GEPGDVQEMPAPESPPGRDP AANLSLALPDDDGSDDSSPP SASPAESEPQCDPSFKGDAG ENTALLEAGRSDSRHGGPIS |
| Function | E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation. |
| Protein Name | E3 Ubiquitin-Protein Ligase Rnf149Dna Polymerase-Transactivated Protein 2Ring Finger Protein 149Ring-Type E3 Ubiquitin Transferase Rnf149 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Rnf149 antibodyAnti-Dna Polymerase-Transactivated Protein 2 antibodyAnti-Ring Finger Protein 149 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Rnf149 antibodyAnti-RNF149 antibodyAnti-DNAPTP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
