Anti-RHOT2 antibody (340-550) (STJ25355)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RHOT2 (340-550) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RHOT2 |
| Gene ID | 89941 |
| Uniprot ID | MIRO2_HUMAN |
| Immunogen Region | 340-550 |
| Immunogen Sequence | PWGPELPRTVRTEAGRLPLH GYLCQWTLVTYLDVRSCLGH LGYLGYPTLCEQDQAHAITV TREKRLDQEKGQTQRSVLLC KVVGARGVGKSAFLQAFLGR GLGHQDTREQPPGYAIDTVQ VNGQEKYLILCEVGTDGLLA TSLDATCDVACLMFDGSDPK SFAHCASVYKHHYMDGQTPC LFVSSKADLPEGVAVSGPSP AEFCRKHRLPA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 340-550 of human RHOT2 (NP_620124.1). |
Additional Info
| Tissue Specificity | Ubiquitously expressed. Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. |
| Post Translational Modifications | Ubiquitinated by PRKN in a PINK1-dependent manner, leading to its degradation. |
| Function | Atypical mitochondrial nucleoside-triphosphatase (NTPase) involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Can hydrolyze GTP. Can hydrolyze ATP and UTP. |
| Protein Name | Mitochondrial Rho Gtpase 2Miro-2Hmiro-2Ras Homolog Gene Family Member T2 |
| Database Links | Reactome: R-HSA-9013419 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinColocalizes With Mgarp And Rhot2 At The Mitochondria |
| Alternative Antibody Names | Anti-Mitochondrial Rho Gtpase 2 antibodyAnti-Miro-2 antibodyAnti-Hmiro-2 antibodyAnti-Ras Homolog Gene Family Member T2 antibodyAnti-RHOT2 antibodyAnti-ARHT2 antibodyAnti-C16orf39 antibody |
Information sourced from Uniprot.org