| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PYCR3 |
| Gene ID: | 65263 |
| Uniprot ID: | P5CR3_HUMAN |
| Immunogen Region: | 13-286 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 13-286 of human PYCRL (NP_075566.2). |
| Immunogen Sequence: | MAAAEPSPRRVGFVGAGRMA GAIAQGLIRAGKVEAQHILA SAPTDRNLCHFQALGCRTTH SNQEVLQSCLLVIFATKPHV LPAVLAEVAPVVTTEHILVS VAAGVSLSTLEELLPPNTRV LRVLPNLPCVVQEGAIVMAR GRHVGSSETKLLQHLLEACG RCEEVPEAYVDIHTGLSGSG VAFVCAFSEALAEGAVKMGM PSSLAHRIAAQTLLGTAKML LHEGQHPAQLRSDVCTPGG |
| Function | Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate (P5C) to L-proline using NAD(P)H. Proline is synthesized from either glutamate or ornithine.both are converted to P5C, and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCR3 is exclusively linked to the biosynthesis of proline from ornithine. |
| Protein Name | Pyrroline-5-Carboxylate Reductase 3P5c Reductase 3P5cr 3Pyrroline-5-Carboxylate Reductase-Like Protein |
| Database Links | Reactome: R-HSA-8964539 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Pyrroline-5-Carboxylate Reductase 3 antibodyAnti-P5c Reductase 3 antibodyAnti-P5cr 3 antibodyAnti-Pyrroline-5-Carboxylate Reductase-Like Protein antibodyAnti-PYCR3 antibodyAnti-PYCRL antibody |
Information sourced from Uniprot.org
