Anti-PTPRZ1 antibody (122-171 aa) (STJ95268)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PTPRZ1 at the amino acid range 122-171
General Information
| Short Description | Rabbit polyclonal anti-Receptor-type tyrosine-protein phosphatase zeta (122-171 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PTPRZ1 |
| Gene ID | 5803 |
| Uniprot ID | PTPRZ_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PTPRZ1 at the amino acid range 122-171 |
| Immunogen Region | 122-171 aa |
| Specificity | PTP Zeta Polyclonal Antibody detects endogenous levels of PTP Zeta protein. |
Additional Info
| Function | Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades. |
| Protein Name | Receptor-Type Tyrosine-Protein Phosphatase ZetaR-Ptp-ZetaProtein-Tyrosine Phosphatase Receptor Type Z Polypeptide 1Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 2R-Ptp-Zeta-2 |
| Database Links | Reactome: R-HSA-449836Reactome: R-HSA-9851151 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinSecretedA Secreted Form Is Apparently Generated By Shedding Of The Extracellular DomainIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Receptor-Type Tyrosine-Protein Phosphatase Zeta antibodyAnti-R-Ptp-Zeta antibodyAnti-Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 1 antibodyAnti-Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 2 antibodyAnti-R-Ptp-Zeta-2 antibodyAnti-PTPRZ1 antibodyAnti-HTPZP2 antibodyAnti-PTPRZ antibodyAnti-PTPRZ2 antibodyAnti-PTPZ antibody |
Information sourced from Uniprot.org