| Host: |
Rabbit |
| Applications: |
WB/ELISA/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Receptor-type tyrosine-protein phosphatase zeta (122-171 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PTPRZ1 |
| Gene ID: |
5803 |
| Uniprot ID: |
PTPRZ_HUMAN |
| Immunogen Region: |
122-171 aa |
| Specificity: |
PTP Zeta Polyclonal Antibody detects endogenous levels of PTP Zeta protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human PTPRZ1 at the amino acid range 122-171 |
| Function | Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades. |
| Protein Name | Receptor-Type Tyrosine-Protein Phosphatase ZetaR-Ptp-ZetaProtein-Tyrosine Phosphatase Receptor Type Z Polypeptide 1Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 2R-Ptp-Zeta-2 |
| Database Links | Reactome: R-HSA-201556Reactome: R-HSA-449836 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinSecretedA Secreted Form Is Apparently Generated By Shedding Of The Extracellular DomainIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Receptor-Type Tyrosine-Protein Phosphatase Zeta antibodyAnti-R-Ptp-Zeta antibodyAnti-Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 1 antibodyAnti-Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 2 antibodyAnti-R-Ptp-Zeta-2 antibodyAnti-PTPRZ1 antibodyAnti-HTPZP2 antibodyAnti-PTPRZ antibodyAnti-PTPRZ2 antibodyAnti-PTPZ antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
