Western blot analysis of the lysates from HeLa cells using PTPRZ1 antibody.

Anti-PTPRZ1 antibody (122-171 aa) (STJ95268)

SKU:
STJ95268
€60.00 - €315.00
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Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Receptor-type tyrosine-protein phosphatase zeta (122-171 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTPRZ1
Gene ID: 5803
Uniprot ID: PTPRZ_HUMAN
Immunogen Region: 122-171 aa
Specificity: PTP Zeta Polyclonal Antibody detects endogenous levels of PTP Zeta protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human PTPRZ1 at the amino acid range 122-171
Function Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades.
Protein Name Receptor-Type Tyrosine-Protein Phosphatase Zeta
R-Ptp-Zeta
Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 1
Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 2
R-Ptp-Zeta-2
Database Links Reactome: R-HSA-449836
Reactome: R-HSA-9851151
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Secreted
A Secreted Form Is Apparently Generated By Shedding Of The Extracellular Domain
Isoform 2: Secreted
Alternative Antibody Names Anti-Receptor-Type Tyrosine-Protein Phosphatase Zeta antibody
Anti-R-Ptp-Zeta antibody
Anti-Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 1 antibody
Anti-Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 2 antibody
Anti-R-Ptp-Zeta-2 antibody
Anti-PTPRZ1 antibody
Anti-HTPZP2 antibody
Anti-PTPRZ antibody
Anti-PTPRZ2 antibody
Anti-PTPZ antibody

Information sourced from Uniprot.org

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