Host: |
Rabbit |
Applications: |
IHC/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Protein Phosphatase 1 Regulatory Subunit 3c (1-150) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
IHC-P 1:50-1:200IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PPP1R3C |
Gene ID: |
5507 |
Uniprot ID: |
PPR3C_HUMAN |
Immunogen Region: |
1-150 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PPP1R3C (NP_005389.1). |
Immunogen Sequence: |
MSCTRMIQVLDPRPLTSSVM PVDVAMRLCLAHSPPVKSFL GPYDEFQRRHFVNKLKPLKS CLNIKHKAKSQNDWKCSHNQ AKKRVVFADSKGLSLTAIHV FSDLPEEPAWDLQFDLLDLN DISSALKHHEEKNLILDFPQ PSTDYLSFRS |
Post Translational Modifications | Ubiquitinated by NHLRC1/malin in a EPM2A/laforin-dependent manner. |
Function | Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types. |
Protein Name | Protein Phosphatase 1 Regulatory Subunit 3cProtein Phosphatase 1 Regulatory Subunit 5Pp1 Subunit R5Protein Targeting To GlycogenPtg |
Database Links | Reactome: R-HSA-3322077Reactome: R-HSA-3785653 |
Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 3c antibodyAnti-Protein Phosphatase 1 Regulatory Subunit 5 antibodyAnti-Pp1 Subunit R5 antibodyAnti-Protein Targeting To Glycogen antibodyAnti-Ptg antibodyAnti-PPP1R3C antibodyAnti-PPP1R5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance