Anti-PPP1R3C antibody (1-150) (STJ11103977)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Protein Phosphatase 1 Regulatory Subunit 3c (1-150) antibody for use in IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP1R3C |
| Gene ID | 5507 |
| Uniprot ID | PPR3C_HUMAN |
| Immunogen Region | 1-150 |
| Immunogen Sequence | MSCTRMIQVLDPRPLTSSVM PVDVAMRLCLAHSPPVKSFL GPYDEFQRRHFVNKLKPLKS CLNIKHKAKSQNDWKCSHNQ AKKRVVFADSKGLSLTAIHV FSDLPEEPAWDLQFDLLDLN DISSALKHHEEKNLILDFPQ PSTDYLSFRS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PPP1R3C (NP_005389.1). |
Additional Info
| Post Translational Modifications | Ubiquitinated by NHLRC1/malin in a EPM2A/laforin-dependent manner. |
| Function | Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 3cProtein Phosphatase 1 Regulatory Subunit 5Pp1 Subunit R5Protein Targeting To GlycogenPtg |
| Database Links | Reactome: R-HSA-3322077Reactome: R-HSA-3785653 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 3c antibodyAnti-Protein Phosphatase 1 Regulatory Subunit 5 antibodyAnti-Pp1 Subunit R5 antibodyAnti-Protein Targeting To Glycogen antibodyAnti-Ptg antibodyAnti-PPP1R3C antibodyAnti-PPP1R5 antibody |
Information sourced from Uniprot.org