Anti-POU2F3 antibody (1-180) (STJ112094)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal POU2F3 (1-180) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | POU2F3 |
| Gene ID | 25833 |
| Uniprot ID | PO2F3_HUMAN |
| Immunogen Region | 1-180 |
| Immunogen Sequence | MVNLESMHTDIKMSGDVADS TDARSTLSQVEPGNDRNGLD FNRQIKTEDLSDSLQQTLSH RPCHLSQGPAMMSGNQMSGL NASPCQDMASLHPLQQLVLV PGHLQSVSQFLLSQTQPGQQ GLQPNLLPFPQQQSGLLLPQ TGPGLASQAFGHPGLPGSSL EPHLEASQHLPVPKHLPSSG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human POU2F3 (NP_055167.2). |
Additional Info
| Tissue Specificity | Specifically expressed in epidermis and cultured keratinocytes. |
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation. The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues. |
| Protein Name | Pou Domain - Class 2 - Transcription Factor 3Octamer-Binding Protein 11Oct-11Octamer-Binding Transcription Factor 11Otf-11Transcription Factor Pla-1Transcription Factor Skn-1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 2 - Transcription Factor 3 antibodyAnti-Octamer-Binding Protein 11 antibodyAnti-Oct-11 antibodyAnti-Octamer-Binding Transcription Factor 11 antibodyAnti-Otf-11 antibodyAnti-Transcription Factor Pla-1 antibodyAnti-Transcription Factor Skn-1 antibodyAnti-POU2F3 antibodyAnti-OTF11 antibodyAnti-PLA1 antibody |
Information sourced from Uniprot.org