| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-POU2F3 (1-180) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
POU2F3 |
| Gene ID: |
25833 |
| Uniprot ID: |
PO2F3_HUMAN |
| Immunogen Region: |
1-180 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human POU2F3 (NP_055167.2). |
| Immunogen Sequence: |
MVNLESMHTDIKMSGDVADS TDARSTLSQVEPGNDRNGLD FNRQIKTEDLSDSLQQTLSH RPCHLSQGPAMMSGNQMSGL NASPCQDMASLHPLQQLVLV PGHLQSVSQFLLSQTQPGQQ GLQPNLLPFPQQQSGLLLPQ TGPGLASQAFGHPGLPGSSL EPHLEASQHLPVPKHLPSSG |
| Tissue Specificity | Specifically expressed in epidermis and cultured keratinocytes. |
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation. The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues. |
| Protein Name | Pou Domain - Class 2 - Transcription Factor 3Octamer-Binding Protein 11Oct-11Octamer-Binding Transcription Factor 11Otf-11Transcription Factor Pla-1Transcription Factor Skn-1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 2 - Transcription Factor 3 antibodyAnti-Octamer-Binding Protein 11 antibodyAnti-Oct-11 antibodyAnti-Octamer-Binding Transcription Factor 11 antibodyAnti-Otf-11 antibodyAnti-Transcription Factor Pla-1 antibodyAnti-Transcription Factor Skn-1 antibodyAnti-POU2F3 antibodyAnti-OTF11 antibodyAnti-PLA1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
