| Short Description : | Rabbit polyclonal POU2F3 (1-180) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | POU2F3 |
| Gene ID: | 25833 |
| Uniprot ID: | PO2F3_HUMAN |
| Immunogen Region: | 1-180 |
| Immunogen Sequence: | MVNLESMHTDIKMSGDVADS TDARSTLSQVEPGNDRNGLD FNRQIKTEDLSDSLQQTLSH RPCHLSQGPAMMSGNQMSGL NASPCQDMASLHPLQQLVLV PGHLQSVSQFLLSQTQPGQQ GLQPNLLPFPQQQSGLLLPQ TGPGLASQAFGHPGLPGSSL EPHLEASQHLPVPKHLPSSG |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human POU2F3 (NP_055167.2). |
| Tissue Specificity | Specifically expressed in epidermis and cultured keratinocytes. |
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation. The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues. |
| Protein Name | Pou Domain - Class 2 - Transcription Factor 3Octamer-Binding Protein 11Oct-11Octamer-Binding Transcription Factor 11Otf-11Transcription Factor Pla-1Transcription Factor Skn-1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 2 - Transcription Factor 3 antibodyAnti-Octamer-Binding Protein 11 antibodyAnti-Oct-11 antibodyAnti-Octamer-Binding Transcription Factor 11 antibodyAnti-Otf-11 antibodyAnti-Transcription Factor Pla-1 antibodyAnti-Transcription Factor Skn-1 antibodyAnti-POU2F3 antibodyAnti-OTF11 antibodyAnti-PLA1 antibody |
Information sourced from Uniprot.org
![Confocal immunofluorescence analysis of HeLa cells using [KO Validated] HNRNPA2B1 Rabbit polyclonal antibody (STJ24063) at dilution of 1:400. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/99826/385443/STJ24063_1__97324.1713154337.jpg?c=1 "Confocal immunofluorescence analysis of HeLa cells using [KO Validated] HNRNPA2B1 Rabbit polyclonal antibody (STJ24063) at dilution of 1:400. Blue: DAPI for nuclear staining.")
