• STJ70457 staining (1. 5µg/ml) of Human Heart lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-ORP2 antibody (C-Term) (STJ70457)

SKU:
STJ70457-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-ORP2 (C-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-Recommended for use at 1-2µg/ml
ELISA-antibody detection limit dilution 1:8000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: OSBPL2
Gene ID: 9885
Uniprot ID: OSBL2_HUMAN
Immunogen Region: C-Term
Accession Number: NP_055650.1; NP_653081.1
Specificity: This antibody is expected to recognise both reported isoforms (represented by NP_055650.1 and NP_653081.1)
Immunogen Sequence: YFERNFSDCPDIY
Function Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro).
Protein Name Oxysterol-Binding Protein-Related Protein 2
Orp-2
Osbp-Related Protein 2
Database Links Reactome: R-HSA-192105
Cellular Localisation Cytoplasm
Cytosol
Lipid Droplet
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Detected On The Surface Of Cytosolic Lipid Droplets
Recruited To The Cell Membrane By Phosphatidylinositol-Phosphate Binding
Alternative Antibody Names Anti-Oxysterol-Binding Protein-Related Protein 2 antibody
Anti-Orp-2 antibody
Anti-Osbp-Related Protein 2 antibody
Anti-OSBPL2 antibody
Anti-KIAA0772 antibody
Anti-ORP2 antibody

Information sourced from Uniprot.org

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